Handwritten Web Interfaces
Holy kamote (again)!DUB - DENIM! An Informal Tool For Early Stage Web Site and UI Design. Available in Windows, Unix, and OS X. (Courtesy of Java's WORA). Check out the video. That was a very slick wacom tablet used for "drawing" the web interface there! More awesome was the fact that the system was able to understand his handwritting.
Someday interface designers are going to rule the application development landscape. Hopefully that leaves a few highly skilled backend developers benefiting from the enevitable scarcity.